N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride
- Product Name
- N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride
- CAS No.
- 478341-55-8
- Chemical Name
- N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride
- Synonyms
- CP-339818;CP-339818 >=98% (HPLC)
- CBNumber
- CB02755856
- Molecular Formula
- C21H25ClN2
- Formula Weight
- 340.9
- MOL File
- 478341-55-8.mol
N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride Property
- storage temp.
- 2-8°C
- solubility
- DMSO: >10mg/mL
- form
- powder
- color
- white to off-white
- Water Solubility
- Soluble to 20 mM in water
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- C2499
- Product name
- CP-339818
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- C2499
- Product name
- CP-339818
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $505
- Updated
- 2024/03/01
- Product number
- C781433
- Product name
- CP339818Hydrochloride
- Packaging
- 5mg
- Price
- $415
- Updated
- 2021/12/16
- Product number
- B6721
- Product name
- CP339818hydrochloride
- Packaging
- 50mg
- Price
- $1158
- Updated
- 2021/12/16
- Product number
- B6721
- Product name
- CP339818hydrochloride
- Packaging
- 10mg
- Price
- $276
- Updated
- 2021/12/16
N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride Chemical Properties,Usage,Production
Biochem/physiol Actions
CP-338818 blocks both Kv1.3 and Kv1.4. Kv1.3 is expressed in brain and in effector memory T (Tem) cells, and Kv1.4 is expressed in brain cells. Kv1.3 and Kv1.4 are members of the Shaker family of voltage-gated potassium channels. Both channels are involved in setting the membrane potential of neurons. In addition, Kv1.3 maintains the membrane potential for T memory cells and is up-regulated upon T cell activation, contributing to multiple immune processes and disorders. Blockers of Kv1.3 have long been sought for therapeutic benefit, and they are also valuable tools for studying the immune system. CP-339818 is valuable for immune system studies, where the absence of Kv1.4 makes it functionally selective for Kv1.3, and it has shown suppression of T cell activation. CP-339818 is also valuable for the study of Kv1.4 function.
N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride Suppliers
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- +1-781-999-5354 +1-00000000000
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- Country
- United States
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